Like, Say if you are hardcore Macromedia Dreamweaver user you will hardly be impressed with Bluefish editor .
So don't loose hope, you can use WINE to get windows applications running directly in Linux. Not all windows applications run. Accordingly to me , rule_of_thumb is , 1 yr or 2 yr old apps will run with WINE, there is list of them at http://appdb.winehq.org .
I had to run following command to get WINE.
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sudo yum install wine
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Now at my Fedora 7 distro on Laptop , I will try to install Dreamweaver trial version. Do i succeed? you can check the video to find out.
NOTE:- like WINE is for old games and windows applications, there is another linux package called Cedega from Transgaming to run DirectX9 windows games on Linux.